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Call: IST-2004-2.4.11 Integrated biomedical information for better health
Priority: Sixth Framework Programme, Priority 2, Information Society Technologies
Type: Specific targeted research project
Start date: April 2006
End date: March 2009
Total R&D costs: 2.6M EUR
EC contribution: 2.2M EUR
Sealife leaflet: pdf doc
Participants:
- 1. Michael Schroeder, Biotec, TU Dresden, Germany
- 2. Albert Burger, Dept. of Computing, Heriot-Watt University, Edinburgh, UK
- 3. Patty Kostkova, City eHealth Research Center, City University, London, UK
- 4. Robert Stevens, BioHealth Informatics Group, University of Manchester, UK
- 5. Bianca Habermann, Scionics, Dresden, Germany
- 6. Olivier Corby, Edelweiss research team, Inria Sophia-Antipolis, France
Prof. Dr. Michael Schroeder
Biotec, TU Dresden
Tatzberg 47-51
01307 Dresden, Germany
Tel: 0049 351 463 400 60
Fax: 0049 351 463 400 61
Email: ms@biotec.tu-dresden.de
Objective:
The objective of Sealife is the conception and realisation of a semantic Grid browser for the Life Sciences, which will link the existing Web to the currently emerging eScience infrastructure. The Sealife browsers allow users to automatically link a host of Web servers and Web/Grid services to the Web content he/she is visiting. This is accomplished using eScience's growing number of Web/Grid Services and its XML-based standards and ontologies. The browsers identify terms in the pages being browsed through the background knowledge held in ontologies. Through the use of Semantic Hyperlinks, which link identified ontology terms to servers and services, the Sealife browsers offer a new dimension of context-based information integration.
The Sealife browsers will be demonstrated within three application scenarios in evidence-based medicine, literature and patent mining, and molecular biology, all relating to the study of infectious diseases. The three applications vertically integrate the molecule/cell, the tissue/organ and the patient/population level by covering the analysis of high-throughput screening data for endocytosis (the molecular entry pathway into the cell), the expression of proteins in the spatial context of tissue and organs, and a high-level library on infectious diseases designed for clinicians and their patients.
To achieve maximum impact, Sealife has put together an advisory board with members from the World Wide Web Consortium, Pfizer, AstraZeneca, Unilever, the UK's National Health Service and the Public Health Agency of Canada. Together, Sealife members and its board will showcase the opportunities presented by building user facing generic tools over semantically rich eScience infrastructure.
Sealife is built on existing tools developed by its partners:
- Dresden: GoPubMed, an ontology-based search engine for the life sciences
- Manchester: COHSE, a Conceptual Open Hypermedia Service which provides GeneOntology annotations for free text and MyGrid for life science web services
- London: NeLI, the National electronic Library for Infection
- Edinburgh: EMAP, the Edinburgh Mouse Atlas Project (MRC Human Genetics Unit)
- Inria Sophia-Antipolis: CORESE, the COnceptual REsource Search Engine
Sealife Browsers:
The Sealife project aims at developing Semantic Grid browsers for the Life Sciences which link the existing Web to the currently emerging eScience infrastructure, thus creating a Semantic Web on top of the existing Web.
Ontologies and controlled vocabularies form the main source of knowledge repositories as input for Sealife browsers.
Such browsers allow users to automatically link a host of Web servers and Web/Grid services to the Web content they are visiting, allowing for further processing. This is accomplished by using eScience’s growing number of Web/Grid Services and its XML-based standards and ontologies.
The browsers identify terms in the pages being browsed through the background knowledge held in ontologies. Through the use of semantic hyperlinks, which link identified ontology terms to servers and services, the Sealife browsers offer a new dimension of context-based information integration.
The Sealife browsers and relevant work developed by all partners under the Sealife project are the following:
, an ontology-based search engine for the web.
For more details on the project, the work performed during its 3 years of duration, the results and the impact of Sealife on research and industry, read the final activity report.
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© SEALIFE
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